Introduction– Many individuals and couples think about wanting a family and try to have one too- but due to a variety of circumstances, they may not be able to conceive. Thankfully, there is no need to worry too much or feel bad in any way- as ART or assistive reproductive technologies are available, for such precise instances. If you have been wondering about starting a family soon, talk to the fertility specialists at Feminova Clinic- as we are the best fertility clinic in Hyderabad. It is however important to know how these fertility treatments work and what factors influence their success rates. So, read on to understand them better. 

Fertility Treatment Success Rates- What Does It Mean?

The percentage of cycles of treatment that result in a live birth- that is basically what the success rate of a fertility treatment is. So, the first such metric that comes to mind is a live birth, when IVF is considered. 

Success Rates for Different Fertility Treatments- 

Success rates of procedures can be measured at different stages or at different points of the treatment you choose to undergo. Some treatment options include-

• IVF- In-vitro fertilisation is the most well known fertility treatment. Studies in India have shown that the success rate is about 30-50% per cycle, while it is higher when women under 35 years of age use their own eggs for the process. Generally speaking, success rates drop as age increases, though this can be circumvented by using a donor egg in most cases. 

Success Rates by Age Group (By Approximation)-

• Below 35: 50% – 70%
• 35–37: 35% – 45%
• 38–40: 20% – 30%
• Above 40: 5% – 20%
• IUI- Intrauterine insemination- This is much more economical and is one of the first options a specialist will ask you to try. Healthy sperm are placed directly in a woman’s uterus, when she is or about to ovulate. This is so the chances of fertilisation occurring are higher than average. Studies have shown that for women under 35, the success rate of this procedure is 10-20% per cycle. This number can drop if age is high or male factor infertility is present. With IUI, chances improve with subsequent cycles- so, if you undergo 3-6 cycles, for example, the cumulative success is well above 60% in some cases. 

Success by Age Group (By Approximation)-

• Below 35: 20% – 25%
• Above 40: 5% – 10%

• ICSI- Intracytoplasmic sperm injection– the success rate of this procedure is pretty high. On average, it is around 40-60% for younger women and lower for women above 40. This is the best treatment if male factor infertility is present. 

Key ICSI Success Rates by Age (Per Cycle)

• Under 35: 45% – 55%
• 35–37: 35% – 45%
• 38–40: 25% – 35%
• 41–42: 15% – 25%

• The usage of donor egg or sperm IVF- This is recommended if couples or individuals are slightly older, or if there are other issues involved. The success rate is much better simply because donor eggs or sperm are taken from younger, more healthy volunteers. The live birth rate is around 50% for this approach, regardless of the age of the woman who opts for this treatment. 

• Fertility Medications – The use of Gonal-F or Menopur is done for stimulating ovulation. Studies have shown it is around 50% or above for women below 35 years of age. This decreases to around 10-20% for women over 40. Donor egg cycles yield high success rates of around 75-85%.  

Key Success Rate Factors (Per Cycle):

• Age <35: 40%–55%
• Age 35–37: 30%–40%
• Age 38–40: 20%–35%
• Age >40: 5%–20%
• Overall/Cumulative: First-cycle success is 35%–45%, while success rates increase to 70%–80% over three cycles.

Conclusion– Apart from choosing the right treatment, it is crucial to make sustainable lifestyle changes for the long term. You should eat healthy food, get enough exercise, learn how to manage stress better and make sure to sleep an average of 7-9 hours every day. These can significantly improve hormonal balance in the body, subsequently helping improve fertility treatment outcomes too. If you have been searching for ‘best IVF clinic near me’ or ‘best gynecologist near me’ online, then walk in to the Feminova Clinic at Nallagandla, Hyderabad, today! Call us for a consultation now! 

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Introduction– Planning to conceive and raise a family are very personal goals and now more than ever, many women and men prefer to take their time to think about it in detail, before rushing into it. This is very relevant- as it is a big emotional and financial decision, with several other motivations which may not be apparent on the surface. When you have a partner, or are not sure about wanting to start a family right away- it makes sense to understand how the biological clock works with respect to overall health and fertility. It can also be hard to really pay attention to subtle signs or symptoms which may point towards infertility and hence diagnosis and treatment may get delayed. This can be problematic for the future- when you do actually want to conceive. So, let us look at the different instances which may necessitate a visit to the best IVF clinic in Hyderabad. 

When To Consult A Fertility Specialist for Infertility?

Here are a few examples of situations which warrant a visit to a fertility specialist- 

• Unprotected sex for some time– For women more than men, the biological clock is pretty unforgiving- as egg quality and number begin to decrease drastically once they hit their late 30s or early 40s. So, if you have had unprotected intercourse for over a year and still have not gotten pregnant (if you are below 35 years of age) or if you are above 35 and have not been able to get pregnant in 6 months under similar circumstances, you should talk to a gynecologist immediately. If you are above 40, then walk into our clinic today, without any further delay! 

• Previous miscarriages- If you have had 2 or more miscarriages before, it is time to talk to a fertility specialist- as it may be an issue that can be medically or surgically corrected. Miscarriages can occur when there is a genetic anomaly, autoimmune issues, severe hormonal imbalance and even uterine malformations which may not be known initially. 
• Pelvic surgery or disease- If you have had previous surgeries, then extensive scar tissue formation can hinder conception by causing the fallopian tubes to get blocked or can interfere with implantation in the uterus. Frequent STIs, even if treated or if there is a delay in treatment can affect the fallopian tubes and consequently impact egg quality too. 
• Issue with erection or ejaculation- Men and their sperm are as important to consider, as women when it comes to egg quality and health. The onus of conception does NOT lie with women alone. So, when men are not able to achieve an erection or are not able to ejaculate normally, it can interfere with conception. Sperm quality is also very important, as is motility, structure and its ability to survive in the female reproductive tract- as only then fertilisation will be possible. If there is any issue here, then you should talk to a male fertility specialist immediately, instead of rushing to judgement. 
• Autoimmune disease- Issues like hypothyroidism, lupus or rheumatoid arthritis can wreak havoc in your body as the immune system is working overtime. It can also impact fertility, so talk to a specialist soon if you have already been diagnosed with an autoimmune condition. 

• Cancer diagnosis and subsequent chemotherapy– If you have cancer and need to undergo radiation therapy or chemotherapy, you should think about freezing your eggs or sperm- so you can keep the possibility of having a family open in the future. 
• Premature menopause– You should talk to a gynecologist if there is a history of premature menopause in your family. 
• PCOS– Hormonal imbalance can affect your ability to conceive, so you should talk to our endocrinologists, as we offer the best PCOS treatment in Hyderabad. 
• Endometriosis and fibroids– When the endometrial lining begins to grow in other places apart from the uterus, it can cause pain, bleeding and affect ovulation. Fibroids are benign tumours which need to be checked on time. 
• Primary ovarian insufficiency (POI)– After 40 years of age, the ovaries don’t function as well as before and this can impact your ability to conceive. So, IVF or using a donor egg may be more suitable in such cases. 

It is best if you do not delay infertility screening- as fertility and age are inversely proportional. Though talking to a fertility specialist may seem daunting, you should consider not letting your preconceived notions get the better of you. Talking to a non-judgemental gynecologist can help a lot in such cases- as they will be able to diagnose the exact issue and come up with a personalized treatment plan, so you can get better. If you have been searching for a male fertility clinic near me or a fertility centre near me, stop overthinking and walk into Feminova Clinic today, for a consultation! 

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Introduction

Unexplained infertility literally means that the specific cause for infertility is not known. Even when individuals feel fine and are actually healthy- preliminary test results say the same, they may not be able to conceive. The catch in this situation is that even detailed fertility tests reveal no abnormalities with respect to structure and egg or sperm quality. Undiagnosed endometriosis, uterine fibroids or polyps may contribute to infertility but at times may not directly influence it either. Hormonal changes also need to occur at the right time and if timing is off, fertility can get affected. Many couples may initially be diagnosed like this but conceive without treatment later on. So, let us look at some causes for idiopathic or unexplained infertility and explore treatment options that are available at the best fertility clinic in Hyderabad. 

Causes for Unexplained Infertility

When a couple has had unprotected sex for over 6-12 months or even longer and are still not able to conceive, a detailed fertility assessment is warranted. Infertility can occur due to a variety of reasons but when evaluations say everything is normal, then it may be called idiopathic or unexplained infertility. Some other reasons include- 

• You may be dealing with an undiagnosed underlying condition which is chronic- like thyroid issues, diabetes, nutritional deficiencies etc.
• For women, egg quality is as important as number- so blood tests need to be done, as imaging can only give a rough estimate of the number of eggs present in the ovaries. Tests check for AMH, FSH, AFC (Antral Follicle Count), Estradiol test (higher levels early in the cycle can correspond to poorer egg quality) and others. Genetic testing may also be recommended in some cases. 
• Women having endometriosis have a harder time conceiving, when compared to other women.
• Quality of cervical mucus- This may seem like a small detail, but if the mucus is too thick or acidic, then sperm cannot move towards the egg and this can hamper fertilization.
• Sperm quality- Just looking for count, motility and structure may not be enough. Detailed quality testing may be necessary – like HBA assay, ROS test, antisperm antibody test, sperm penetration test, sperm DNA fragmentation test etc. respectively. 

Why You May Be Diagnosed With Unexplained Infertility

Here are some reasons as to why you may be diagnosed with unexplained infertility-

For women-

• When you ovulate at regular intervals and your cycle is normal.
• There is no issue or blockage in the fallopian tubes
• Your uterus looks and functions normally – no problem with the endometrial lining. 
• Hormones needed to govern the whole process – from egg release to fertilisation and implantation seem to be in normal range. 
• You have a good ovarian reserve for your age.

For men-

• Sperm count is within range in the sample you have given.
• Sperm motility is good. 
• Shape and structural tests reveal normal results. 

Studies show that about 15-30% of all infertility related cases seeking treatment can be attributed to unexplained infertility in the Indian subcontinent. This is because tests normally check for overt issues. Subtler problems may not be diagnosed in the first pass and will hence require detailed testing. 

Treatment Options for Unexplained Infertility

Some well known treatment options include- 

• Assisted Reproductive Technology– Methods like IUI (intrauterine insemination) and IVF are very well known choices. To help improve fertilisation chances, ICSI (intra-cytoplasmic sperm injection) can be performed- so that sperm can be directly injected into the egg and barriers to fertilisation are overcome much better. ICSI is a great choice when sperm motility or quality is an issue. 
• When you opt for IUI or IVF, you will be given hormonal medications like gonadotropins and clomiphene. Gonadotropins are prescribed to promote follicle development and egg production in women and can help with low sperm count in men. Clomiphene helps increase the number of eggs that will be released in women- which also increases chances of conception. 
• The last way is when the gynecologist asks you to track your cycle closely- using ovulation kits, with basal temperature changes, so you can time intercourse within your fertile window – right before or during the days of ovulation. 

Conclusion

Unexplained infertility as a diagnosis can be hard to understand and deal with- as technically there is no issue but you are still not able to conceive. In such cases, the gynecologist may ask you to continue trying like before. It does you no good to get stressed, so instead- try to pivot and see about making necessary lifestyle changes- like eating nutritious meals, getting enough exercise every week and managing stress actively in different ways. If you would like to get a second opinion, then you should go ahead. If you’d prefer not to wait and instead want to begin fertility treatment without delay, talking to the best IVF doctor in Hyderabad makes total sense. So, call us at Feminova Clinics for a consultation today! 

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Introduction –Conception is a complicated process with a  lot of steps that need to occur perfectly- if even one is slightly off, fertilisation does not occur and conception or having a family can become a distant dream. Male infertility occurs when you have had unprotected intercourse with your partner for the past year, but there has been no change. So, if you have been searching for the ‘best male fertility clinic near me’ online, stop worrying! You have come to the right place! 

Common Causes for Male Infertility

Most of us assume it is easy to have babies but humans are a low reproductive capacity species actually. That is because, for every month a couple has unprotected sex, there is less than 20% chance of conception occurring. With respect to males, these are the possibly problematic aspects you should know of-

• Healthy sperm cells are not being produced.
• Sperm cells produced are healthy but number is low (oligospermia)
• Some men may produce semen which has no sperm cells in it at all (azoospermia).
• The sperm is having motility issues and is not able to move towards the egg. 
• The sperm is able to move but cannot fertilise the egg. 
• If you have unusually low levels of the hormone testosterone. 
• If you suffer from hormonal issues due to thyroid, hypothalamus and pituitary gland conditions. 
• If you have had STIs before or have one at present. 
• If you have an autoimmune condition that causes the immune cells to attack your sperm cells. 
• If there has been some testicular trauma of some kind. 
• If you have swollen veins in the testicles- called varicoceles.
• If you have had radiation therapy for cancer. 

Your semen needs to be thick and sticky, as opposed to thin or runny in texture. This is necessary because the semen provides sperm cells energy, nutrients and a way into the vagina. 

Diagnosis of Male Infertility

A male fertility specialist or endocrinologist can help diagnose male infertility. Apart from taking a detailed medical history and having you answer questions on your sexual habits, these are the following tests that are recommended-

• Semen analysis- to check for number, health and motility of sperm cells. These days, ultra high resolution microscopes provide greater information on sperm cell DNA, fragmentation and amounts of hyaluronic acid present in the cell (as this is important for fertilisation with the egg). 
• Imaging like MRI or ultrasound. 
• Blood tests are done to check for hormone levels. 
• Urinalysis to check for STIs or diabetes. 
• In rare cases, a testicular biopsy is done. 

Advanced tests like PICSI are recommended only when there is fragmentation of DNA or previous IVF cycle failures, as these are more specialised. 

Treatment Options For Male Infertility-

You will be asked to make sustainable lifestyle changes – like eating well, getting regular exercise, not smoking or drinking and avoiding the usage of lubricants during sex. 

Hormone medications are given to deal with any hormonal excesses or deficiencies. Surgery is also an option- for sperm retrieval, treating varicocele if you have one, or removing any blockage in the epididymis.

One of the best approaches for conception to occur include the use of ICSI- Intracytoplasmic Sperm Injection- where the healthiest sperm is selected after semen analysis and is directly injected into a mature egg- to improve chances of fertilisation. So, call us today if you would like to learn more about the best ICSI treatment in Hyderabad. 

If ICSI fails, then IVF may be suggested.

Conclusion– Conception is not an easy process and it takes time. Male infertility treatments thankfully are easy to get these days, as the underlying causes for infertility have been well studied. Once the cause has been diagnosed, you can take requisite medications and change your routine, so you get better. If you want to get treated by experienced specialists at the best fertility clinic in Hyderabad, call us at Feminova Clinics today! We are conveniently located in Nallagandla, Hyderabad. 

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Introduction– Fertility is generally defined as the ability of an individual to conceive or have children. But, the process of conception has many steps, all of which are governed by various hormones and other pathways. If any one of these hormones or pathways don’t work right, then the individual may have to deal with infertility. PCOS is the single most well known cause for wreaking havoc on a woman’s hormonal and reproductive health. If you have been searching for ‘best PCOS clinic near me’ online, then walk in to Feminova Clinic today! 

Hormones Involved in Fertility-

There are many hormones that are necessary for a woman to be able to conceive. Hormone levels are never constant and instead peak and drop – which is how women have menstrual cycles, roughly every month or so. The 4 main hormones that regulate the whole process and reproductive health of a woman include- 

• LH- Luteinising Hormone- This hormone works with FSH during ovulation, by triggering the release of a mature egg from the ovary. When LH levels surge in the middle of your menstrual cycle and this determines the peak of your fertile window. High LH values may indicate PCOS in women. It can lead to missed periods or irregular ovulation. 

• FSH- Follicle Stimulating Hormone – FSH is produced by the pituitary gland. Development and maturation of the ovaries occurs due to FSH in females. Both high and low levels of FSH can be problematic. High FSH levels occur due to primary ovary insufficiency. Low levels of FSH can lead to infertility in both men and women. 

• Oestrogen – Oestrogen is a hormone produced by fat cells, the ovaries and the adrenal glands. Oestrogen levels are the highest in your fertile window. One of its functions is to thin cervical mucus- allowing sperm to make their way to the egg in an easier manner. Oestrogen causes the endometrial lining to grow and thicken every month, so implantation can occur, if fertilisation takes place. Normal oestrogen levels can mean that your menstrual cycle is regular. 

• Progesterone – After the mature  egg has been released, the corpus luteum in the follicle triggers the release of progesterone. This hormone’s levels will continue to increase if fertilisation and implantation occur. But, if fertilisation has not occurred, then the corpus luteum will degenerate, causing progesterone levels to fall, till the next LH surge causes it to increase, in the following cycle. Progesterone levels keep increasing for a few weeks, even after pregnancy has been established. This occurs, so as to allow time for the placenta  to grow. Once the placenta is around 12 weeks, it begins to produce progesterone on its own, which will then continue to sustain the pregnancy till term. 

• Prolactin and TSH issues can also impact fertility in women. 

In men, both FSH and testosterone are important in making sure that enough sperm cells are produced and that they are motile. LH helps in production of testosterone by the testes. If thyroid hormones are affected, then LH, FSH and testosterone action can go haywire. 

Hormonal Imbalance and PCOS-

The 3 hormones- LH, FSH and oestrogen help ovulation and occurrence of monthly menstrual cycles. When the hormones are not in the right levels, you may have to deal with PCOS related symptoms. For men, it can translate to poor sperm quality and low count. 

This hormonal imbalance can impact fertility- as ovulation becomes irregular, egg maturation does not occur, excessive hair growth and symptoms caused by high levels of androgens. 

Conclusion– Hormonal imbalances – either highs or lows can be frustrating to deal with- as they can impact fertility negatively. But there is no need to despair. You will need medication and have to make lifestyle changes- so that hormone levels get back within range. You will need specialised PCOD treatment in Hyderabad, if you have not been able to conceive. So, walk in to the Feminova Clinic in Nallagandla, as we are the best fertility clinic in Hyderabad. Call us today! 

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Introduction- Every parent wants to have a hearty and healthy child, with no abnormalities or disorders. This is where PGD comes in. In natural conceptions, prenatal tests are done to identify genetic abnormalities while in IVF conceptions, pre-implantation genetic screenings are done to identify abnormalities in fertilised embryos.  These tests are legal and are available in most fertility centres. Specialised techniques like biopsy of embryo and subsequent genetic analysis using techniques like PCR, FISH or CGH is done for identification of normal, healthy embryos – all in an effort to prevent miscarriages from occurring in the future, or to prepare you for any other eventuality. Cost can vary according to the area and centres and it requires a significant amount of financial investment in some cases. The use of PGD as a mode of screening is increasing in India, as there is greater willingness to try IVF and other ART methods, if natural conception is not happening. 

What Is A Pre-Implantation Genetic Diagnosis (PGd) And Its Types?

Pre implantation genetic diagnoses are a series of testing done on embryos which are fertilized through IVF, for screening genetic disorders or chromosomal abnormalities before transferring it to the mother. It helps your family to ensure and aim for healthy children, free from disorders by ending the familial history of genetic transmission of diseases. 

Different types of PGD’s:

There are 2 main types:

• PGD for monogenic disorders/ PGT-M: This type of pre implantation genetic diagnosis is useful in detecting diseases of a single gene type; it is clear, specific and widely accepted. Helps in anomaly detection even before implantation in the uterus. These tests are recommended to couples with strong family traits of genetic anomalies identifying the possible percentage of anomaly transfer. For this test, the parents must initially undergo genetic testing to identify the error or mutation in the gene. Once the results are obtained,  the embryos are diagnosed appropriately for those specific genetic anomalies making it easier for designing IVF protocols. 
• PGS/PGT-A: This technique is used to select embryos with the right chromosomal number (euploidy), as this can determine its capability for implantation in the uterus. Embryos with higher or lower number of chromosomes (aneuploidy)  may not implant correctly leading to pregnancy loss. It is specifically done for mothers of advanced age or with a recurrent history of miscarriage or failed IVF cycles. 

What Is Analysed Using Pgd?

PGD is used for analysing chromosomal conditions in families where-

• One partner in the couple has a dominant gene of a genetic disorder; there is a 50% chance of their future offspring having the same genetic mutation. 
• The mother is a carrier – she may or may not transfer the defective gene to her offspring and there is still a 50% chance of inheritance, depending on the gender of the child. 
• Both the parents are genetically recessive – then there is about a 25% chance that their future offspring may be affected, and have both copies of the recessive gene- leading to the condition. 

Conclusion– Pre-implantation genetic testing or diagnosis is an advanced science in the field of in-vitro fertilization. All the embryos produced through IVF may not be healthy and couples with a history of delayed fertility or genetic anomalies tend to face miscarriages. In such cases, PGD is more like a safe precaution and a confirmation if their embryo or future offspring can lead a healthy life or not. The decision can be made by the parents if they’re willing to take a chance with children who are genetically abnormal. This kind of diagnosis helps the couple to have a happy and healthy family. If they’re carriers of recessive genes, this procedure can help their off-springs and the future generations to be free from such genetic anomalies. These tests are conducted under the guidance of experienced doctors and IVF specialists in fully equipped fertility hospitals or clinics. 

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